Desogestrel, ethinyl estradiol



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Desogestrel, ethinyl estradiol


Isibloom is a combined pill. It’s super-effective at preventing pregnancy (over 99%).

Subscribe to get your birth control taken care of. Buy Isibloom online and get regular refills from a US pharmacy when you need them.

From only $8.04 per month


Protection against getting pregnant, with minimal fuss. That’s what you get with combined pills like Isibloom. It’s a once-daily pill you take for 28 days before starting a new pack.

You know what makes birth control even less fussy? Getting it delivered to your door, by subscription, from a US pharmacy. Or, a quicker way of saying that: getting it from EveAdam.

Take a consultation to see what our prescriber thinks is the best pill for you. Then choose from the suggestions and set your schedule. You’ll get your first delivery in 2-5 working days, and follow-up deliveries when you need them.

What is the Isibloom pill?

A combined pill packing two hormones that help stop you getting pregnant. They do this by fooling the body into thinking it’s already ovulated, so it doesn’t ovulate. These hormones also change the texture of the uterine wall, so any stray fertilized eggs can’t catch on there and develop. They also alter the consistency of the mucus that’s released in the cervix so sperm can’t shoot through.

So two hormones, doing three jobs.

Some women also take combined pills like Isibloom for acne, as a kind of secondary reason (in addition to preventing pregnancy).

How effective is Isibloom?

Over 99%. We know, over 99% should technically be 100%. But it’s only “over 99%” because it’s somewhere between 99 and 100. This means that out of 100 women taking the pill, over a year, fewer than one will get pregnant.

That’s with perfect use by the way. So taking it every day, like you’re supposed to, and not making any mistakes. Making the occasional error when taking the pill reduces this rate of effectiveness a little, to around 91%.[1] So it’s best to take it like it says.

What dosages of Isibloom tablets are there?

Just the one. It’s a pretty common formulation you can get in other pills. If you want to switch doses, you’ll need to move on to a different pill, because there’s no Isibloom Lo.

Viorele, Velivet and Mercette are very like Isibloom, only with less estrogen. So if you get side effects like vaginal dryness, mood swings or low sex drive, you might be better on a lower estrogen dose. The licensed doctor can help you find the right pill during your consultation.

Page reviewed by:
Dr Bruce Oran
Dr Bruce Oran
Senior Medical Adviser
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Last updated November 1, 2021


What is Isibloom used for?

Contraception primarily. It’s very effective at this (over 99% when taken right). It’s quite flexible in that, compared to other forms of birth control, it’s both reliable and reversible. So you can stop taking Isibloom any time to start trying for a baby.

It may also help to reduce the symptoms of PMS (premenstrual syndrome) and treat acne.

Can you take Isibloom for acne?

How does Isibloom work?

How to get Isibloom online

How to take Isibloom

Isibloom is a 28-day pill. You’ll take one active pill, once a day, at the same time, for 21 days continuously. Then you have seven days of inactive pills, move onto the next pack and repeat.

It’s best to work taking the pill into your routine, so you’re less likely to forget it. For example, you might take it before going to bed, or before you brush your teeth in the morning. Just make sure you pick a time that works for all seven days of the week.

When to start Isibloom

Taking Isibloom after pregnancy

What to do if you miss a Isibloom pill

When to see a doctor about side effects

It’s rare that serious side effects occur on the combined pill. But it’s still important to be mindful of these and get help if you notice anything unusual.

Before taking this pill, refer to the package insert that comes with the medication for detailed info on side effects and what to do if you notice them.

If you experience any of the following, seek immediate medical attention:

Deep vein thrombosis: pain in the leg that occurs when standing, a warm feeling in the affected leg and a bluish colour on the leg.

Pulmonary embolism: breathlessness, coughing that brings up blood, chest pains, dizziness, irregular heartbeat and stomach pains.

Retinal vein thrombosis: pain in the eye, blurred vision and loss of vision.

Heart attack: chest pain, a feeling of fullness or squeezing in the chest or arm, indigestion with a feeling of choking, back discomfort that radiates to the stomach, jaw, throat and arm, sweating, nausea, dizziness, vomiting, weakness, anxiety, loss of breath and irregular heartbeat.

Stroke: weakness, numbness in the face or limbs, problems speaking, confusion, vision problems, loss of balance, severe headaches and fainting or seizures.

Are there other pills that are similar to Isibloom?

What are the most common side effects on Isibloom?

Some more common side effects reported among women using Isibloom include: headaches, weight gain, mood changes, tender breasts and digestive issues. Milder side effects will tend to pass after you’ve been using Isibloom for a few months. But if you find that these stick around for longer, let us know. The licensed doctor might be able to suggest an alternative treatment that works better for you.

Is there a non-pill alternative to Isibloom?

Is Isibloom the same as Apri?


It is important that you read the patient information insert that comes with your medication before you start this treatment. If in doubt, ask the doctor during your consultation.

If you’re uncertain about anything at all, our doctor should be able to help. Just let them know.

More information

When you shouldn’t use Isibloom

Use of Isibloom should be avoided if you have any of the following:

A history of blood clots, health issues that affect clotting (such as certain protein deficiencies), conditions that leave you bed bound or off your feet for large portions of the day, angina, severe hypertension, high fat levels in the blood, migraines with aura, severe liver disease, liver tumors, pancreatitis, pregnancy, certain cancers, unexplained vaginal bleeding and allergies to any of the medication’s ingredients.

Isibloom warnings and cautions

Taking Isibloom with other medications


[1] Kost,K, Et al. 2008. Estimates of contraceptive failure from the 2002 National Survey of Family Growth. U.S.A. N.I.H.

[2] Jaisarmarn, U Et al. 2014. A comparison of multiphasic oral contraceptives containing norgestimate or desogestrel in acne treatment: a randomized trial. National Library of Medicine. USA.