Norgestimate, ethinyl estradiol



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Norgestimate, ethinyl estradiol


Tri-Sprintec is a combined hormonal birth control pill. When you take it, it’s very unlikely that you’ll get pregnant. There’s also a lower dose variation called Tri-Lo-Sprintec.

With EveAdam, you can buy Tri-Sprintec online and have it shipped to you regularly from a US pharmacy.

From only $11.35 per month


Tri-Sprintec is a type of birth control pill. It’s a “combined pill” and contains two hormones that work in the body like progesterone and estrogen. When you take Tri-Sprintec tablets correctly, your chances of getting pregnant are very small — less than 1%.

There’s a lower dose version too, called Tri-Lo-Sprintec (aka Tri-Sprintec Lo).

Getting a birth control prescription through EveAdam is easy and fast. After a consultation with a licensed doctor, you’ll pick how often you want to receive your refills and we’ll get our preferred pharmacy to fill your prescription and pop it in the mail. It’s all online — no awkward phone calls or annoying trips to the pharmacy. Try us out today and start your consultation.

How does Tri-Sprintec birth control work?

The two hormones in Tri-Sprintec trick the body into not making the necessary preparations to become pregnant. They stop the ovaries from releasing an egg, and try to block sperm from reaching and fertilizing the egg by thickening the fluid in the womb.

Taking the combined pill also stops your uterine wall from becoming thicker every month. When it stays thin, it’s not as easy for a fertilized egg to attach to the wall and grow. This effect can also mean you’ll get lighter or more regular periods.

There are 28 Tri-Sprintec tablets in each pack: 7 gray pills, 7 light blue pills, 7 blue pills and 7 white (inactive) pills. All you need to do is take the pills at the same time every day, in this order, and repeat every 28 days (so on the plus side, there are no breaks to remember).

How is Tri-Lo-Sprintec different?

There is a Tri-Sprintec Lo dosage for women who have a slight estrogen sensitivity. The pills are very similar, but the active pills in Tri-Lo-Sprintec have a little less estrogen. Women who use Tri-Sprintec but get mild estrogenic side effects may be recommended the “Lo” version by a doctor instead.

Estrogenic side effects are symptoms like nausea, swollen or tender breasts, or heavy menstrual bleeding.

What is the generic name for Tri-Sprintec?

Tri-Sprintec generics (read: pills with the same ingredients) include Ortho Tri-Cyclen, TriNessa, Tri-Previfem, Tri-Linyah, Tri-Estarylla, Tri-Femynor, Tri-VyLibra and Norg-EE.

These pills should work in the same way and be just as effective as Tri-Sprintec. The main differences will be the packaging, how the pills look, who manufactures them (Tri-Sprintec is made by Teva) and normally the price.

Tri-Sprintec is probably the most well-known name for this pill, but Tri-Estarylla is a little cheaper.

Page reviewed by:
Dr Bruce Oran
Dr Bruce Oran
Senior Medical Adviser
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Last updated November 1, 2021


What is Tri-Sprintec?

Tri-Sprintec is a combined oral contraceptive pill (COCP) from Teva. There are two hormones in the pill that slightly change the environment in the body, and make it highly unlikely that you’ll get pregnant. It’s a 28-day pill, which means you take it every day unlike some other birth control pills which have a seven-day break between packs. 

How does Tri-Sprintec work?

What is Tri-Lo-Sprintec?

Can you take Tri-Sprintec for acne?

How effective is Tri-Sprintec?

How to take Tri-Sprintec tablets

Because it’s a triphasic pill, it’s important to take your Tri-Sprintec pills in the order directed on the pack.

You can start taking Tri-Sprintec on any day, but if you take it on the first day of your period, you’ll be covered against pregnancy immediately. If you take it on another day, you’ll need to use condoms for the first seven days while the pill takes effect.

If you’re changing from Tri-Sprintec from another pill, you can start Tri-Sprintec on the day after your last pill in the other pack.

Take one tablet every day at the same time.

You don’t need to take it with food.

Make sure you refer to the instructions in the package insert before you start taking Tri-Sprintec.

What do Tri-Sprintec pill colors mean?

What if I miss a Tri-Sprintec pill?

Can I skip a period with Tri-Sprintec?

What are the most common side effects on Tri-Sprintec?

Headaches are pretty common when taking the birth control pill. Other common side effects include breast tenderness or swelling, increased vaginal discharge and stomach aches.

A lot of the time, women who get these side effects find that they’re mild and pass after a few weeks. But if they persist, or if you get any side effects that are more uncomfortable, let a doctor know. They may be able to help you out by switching you to another pill. On an EveAdam plan, you can do this easily by logging in and leaving the doctor a message.

For any serious side effects, go to the emergency room immediately. You can find more info on when to see a doctor in the package insert.

Does Tri-Sprintec cause weight gain?

Does Tri-Sprintec cause depression?

Will I get breast growth with Tri-Sprintec?

What’s the difference between Sprintec and Tri-Sprintec?

They contain the same hormones, but Tri-Sprintec is a multiphasic pill. Sprintec is a monophasic pill.

In monophasic pills, the amount of hormones delivered into the body stays the same through the four-week cycle. In multiphasic pills, it changes throughout the course of the cycle. Tri-Sprintec has three phases that last for seven days each: gray pills, light blue pills and blue pills.

The gray pills contain 0.18mg norgestimate and 350mcg ethinyl estradiol; the light blue pills contain 0.215mg norgestimate and 350mcg ethinyl estradiol; and the blue pills carry 0.25mg norgestimate and 350mcg ethinyl estradiol. The white pills don’t contain any hormones.

All 21 active pills in a Sprintec pack are blue (and contain the same level of hormones listed in the blue pills above).

Whether you choose a multiphasic or monophasic pill depends on how your body reacts to hormonal birth control. Some women find that they get better control of menstrual symptoms when using a particular kind. Let the doctor know if you’re unsure which type of pill is best for you.

Is there more than one Tri-Sprintec dosage?

What Tri-Sprintec generics are there?


Always read the package insert that comes with your pill before taking it. If there’s anything about taking the pill that you’re unsure about, ask the doctor for help.

Read more birth control safety information

Can Tri-Sprintec interfere with other medications?

The birth control pill can sometimes interact with other medications, and some of them may make Tri-Sprintec less effective. If you’re taking other medications, you shouldn’t stop, but it’s very important to let the doctor know what medication you’re taking (or have recently taken) during your consultation.

Read more about interactions and the combined pill

Can anyone take Tri-Sprintec?


[1] Jaisarmarn, U Et al. 2014. A comparison of multiphasic oral contraceptives containing norgestimate or desogestrel in acne treatment: a randomized trial. National Library of Medicine. USA.

[Accessed 3rd July 2021]

[2] Lindh, I, Et al. 2011. The long-term influence of combined oral contraceptives on body weight. Human Reproduction. U.K. Oxford Academic.

[Accessed 4th July 2021]