From$792.91 per month

  • Free 2-5 day delivery
  • US-licensed physicians



Xenical is a capsule that helps you to lose weight. 

Subscribe to EveAdam to buy Xenical online, and get repeat shipments from a US pharmacy. 

From $792.91 per month

Buy Xenical online with an EveAdam subscription. Weight loss treatment made easy.

We know. Prescriptions can be a chore. 

What is Xenical?

It’s a 120mg weight loss capsule that stops around one third of the fat that you eat from being absorbed by the body. 

You take it at the same time as a meal, three times a day. When you combine it with a balanced and healthy diet as well as exercise, it can help you lose weight.

It’s recommended for people who have a BMI (body mass index) of 30 or above. But it’s also helpful if you have a BMI of 28 or over and also have a medical condition, like diabetes or high blood pressure.

How does Xenical work?

Xenical is a weight loss capsule that joins with enzymes in your digestive system (called lipases) and stops them from breaking down fats into small enough parts so that the body can absorb them. Rather than the body digesting the fat in the food that you consume, this fat is instead removed from the body in your stool (and so you lose weight). 

It sounds a bit out there, we know, but studies have shown that Xenical is effective as part of a weight loss programme [1]

Xenical or Orlistat: what’s the difference?

There isn’t much difference. Xenical is the branded treatment, so it’s more well known than Orlistat, and a little pricier as the more recognised weight loss product. Orlistat, as the generic treatment, is a bit cheaper. The appearance of the tablets, and the packaging they come in, may differ too.

But otherwise, both treatments contain the same active ingredient, orlistat, and work in exactly the same way in the body. 

Page reviewed by:
Mr Craig Marsh
Mr Craig Marsh
Pharmacist Prescriber
Visit author profile
Last updated March 25, 2022


Is Xenical the right weight loss treatment for me?

It could be. Weight loss medications are suitable only for people whose BMI is at least 30 (or 28 if you have other risk factors such as high blood pressure or type 2 diabetes). So it’s important that you check to see what your BMI is first. 

You can use the CDC healthy weight calculator [2] for this. The calculator will reflect if you’re of a healthy weight, and the amount of weight you should aim to lose if you’re overweight. 

Xenical is a capsule treatment, so if capsules are a preferred form of weight loss medication for you, it may be the right fit for you on this basis. If you’re not able to take capsules, or if your personal preference is another form of treatment, Contrave is an option. We also offer Saxenda, which is an injection. 

Whether Xenical is the best weight loss product for you may also depend on your susceptibility to certain side effects, if you have a particular health condition, or if you are currently taking other medication that may interact with Xenical. Our clinician will take these factors into consideration as part of your EveAdam consultation, and determine if it’s a safe and appropriate treatment for you. 

Can I buy Xenical over the counter?

How to get Xenical online

How to take Xenical

You should always take Xenical as instructed by your clinician, and check with them if you’re unsure. 

Take one capsule with each of your three main meals (breakfast, lunch and dinner) every day. You can take it right before your meal, during your meal, or up to one hour after your meal. Swallow the capsule whole with water. 

Xenical is only effective when you eat dietary fat, so if you miss a main meal or if you have a meal that doesn’t contain any fat, you don’t need to take Xenical. 

If you haven’t lost at least 5% of your body weight (as measured at the start of your treatment course) after 12 weeks, the clinician might suggest trying a different medication. 

What to eat when taking Xenical

If I miss a Xenical tablet, what should I do?

How long does Xenical take to work?

Xenical side effects: what are the most common?

Headache, abdominal pain, oily discharge, an urgent or increased urge to open your bowels, flatulence with discharge, liquid stools, fatty or oily stools and low blood sugar levels (which may be experienced by people with type 2 diabetes) are the most common side effects, affecting more than 1 in 10 people. 

What should I do if I get side effects with Xenical?

When should I see a clinician?

Xenical vs Alli: which is better?

They both contain the same active ingredient, orlistat, so both treatments work in the same way. Alli stops about one quarter of the fat that you consume from being digested, whereas Xenical prevents around one third of the fat from being absorbed by the body. Alli also contains half the dosage of Xenical (60mg, as opposed to 120mg), which is why it helps to remove less fat from the body. 

Because Alli isn’t as strong however, it’s available over the counter, so you don’t need a prescription for it. Xenical and Alli are both branded products, but Alli is slightly cheaper.

Given that both treatments work in the same way but are different doses, it’s really a matter of how much weight you’re looking to lose that decides which one you should take. Your clinician can advise you further on both options, and help you to make an informed decision. 

Xenical or Phentermine: what’s the difference?

What should I do if Xenical doesn’t work?


Always read the package insert before taking Xenical. You can read more info about this drug at the link below.

More info

Is Xenical safe to use?

Yes, but it’s not suitable for everyone. 

You shouldn’t take Xenical if: you’re allergic to orlistat or to any other ingredients in Xenical; you have chronic malabsorption syndrome (when nutrients aren’t absorbed sufficiently from the digestive tract); you have cholestasis (liver disorder); or if you’re breastfeeding (it’s not recommended if you’re pregnant either). 

Losing weight can also impact on treatment doses for conditions such as diabetes and high cholesterol. If you’re using these medicines, it’s very important that you speak to your clinician. They may need to change the doses of these treatments.

If you’re using any oral contraceptives, it’s advisable to use additional contraception if you’re taking Xenical, as it can trigger severe diarrhoea, which may compromise the effectiveness of contraception. 

If you have chronic kidney disease, the use of Xenical may be linked to renal stones. So if you have any problems with your kidneys, discuss these with your clinician.

Xenical and contraindications


[1] Suyog S. Jain, Sunita J. Ramanand, Jaiprakash B. Ramanand,1 Pramod B. Akat, Milind H. Patwardhan and Sachin R. Joshi. 2011. Evaluation of efficacy and safety of orlistat in obese patients. NCBI [online]. 2011 Apr-Jun; 15(2): 99–104. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125014/ [Accessed 14 Apr 2021].

[2] Knott, Laurence. (2018). Orlistat Weight Loss Medicine. [online] Patient. Available at: https://patient.info/healthy-living/obesity-overweight/orlistat-weight-loss-medicine [Accessed 14 Apr 2021].